Table II.
Time trends of pathogen-specific healthcare-associated infections at the National Taiwan University Hospital, 1981–2007
| Pathogen | Incidence (per 100 discharges) |
Average annual change, % (95% CI) | P-valuea | |
|---|---|---|---|---|
| 1981 | 2007 | |||
| Staphylococcus aureus | 0.199 | 0.404 | 3.1 (1.9 to 4.3) | <0.0001 |
| Meticillin-resistant | 0.028 | 0.272 | 11.4 (8.3 to 14.6) | <0.0001 |
| Meticillin-susceptible | 0.164 | 0.132 | −2.8 (−3.9 to −1.7) | <0.0001 |
| Enterococcus spp. | 0.004 | 0.452 | 0.2 (−1.8 to 2.2) | 0.8463 |
| Escherichia coli | 0.634 | 0.650 | −0.2 (−1.3 to 0.9) | 0.719 |
| Klebsiella spp. | 0.447 | 0.552 | 0.5 (−0.6 to 1.5) | 0.3683 |
| Enterobacter spp. | 0.299 | 0.356 | 0.0 (−0.6 to 0.6) | 0.9234 |
| Pseudomonas aeruginosa | 0.538 | 0.516 | −1.7 (−2.4 to −1.0) | <0.0001 |
| Acinetobacter spp. | 0.227 | 0.393 | 2.4 (1.4 to 3.4) | <0.0001 |
| Extensively drug-resistant | 0.000 | 0.105 | 75.4 (46.9 to 109.3) | <0.0001 |
| Candida albicans | 0.016 | 0.272 | 7.5 (5.5 to 9.6) | <0.0001 |
CI, confidence interval.
a
Negative binomial regression was used to model the secular trends of the annual incidence.