Table III.
Time trends of pathogen-specific healthcare-associated bloodstream infections at the National Taiwan University Hospital during 1981 and 2007
| Pathogen | Incidence (per 100 discharges) |
Average annual change, % (95% CI) | P-valuea | |
|---|---|---|---|---|
| 1981 | 2007 | |||
| Gram-positive aerobic bacteria | 0.092 | 0.617 | 8.4 (7.0 to 9.8) | <0.0001 |
| Staphylococcus aureus | 0.024 | 0.203 | 10.3 (8.1 to 12.5) | <0.0001 |
| Meticillin-resistant | 0.000 | 0.138 | 23.4 (16.9 to 30.2) | <0.0001 |
| Meticillin-susceptible | 0.020 | 0.066 | 3.0 (1.2 to 4.8) | 0.0009 |
| Enterococcus spp. | 0.000 | 0.180 | 7.85 (6.3 to 9.3) | <0.0001 |
| Gram-negative aerobic bacteria | 0.291 | 1.137 | 5.4 (4.7 to 6.1) | <0.0001 |
| Escherichia coli | 0.048 | 0.180 | 3.3 (2.3 to 4.3) | <0.0001 |
| Klebsiella spp. | 0.076 | 0.246 | 5.8 (4.6 to 7.0) | <0.0001 |
| Enterobacter spp. | 0.048 | 0.166 | 5.2 (3.7 to 6.8) | <0.0001 |
| Pseudomonas aeruginosa | 0.016 | 0.153 | 4.0 (2.9 to 5.0) | <0.0001 |
| Acinetobacter spp. | 0.040 | 0.217 | 7.7 (6.3 to 9.1) | <0.0001 |
| Extensively drug-resistant | 0.000 | 0.045 | 62.1 (37.7 to 90.8) | <0.0001 |
| Anaerobic bacteria | 0.004 | 0.052 | 2.3 (1.0 to 3.6) | 0.0005b |
| Fungi | 0.008 | 0.213 | 15.0 (9.9 to 20.4) | <0.0001 |
| Candida albicans | 0.000 | 0.105 | 13.5 (8.7 to 18.4) | <0.0001 |
a
Negative binomial regression.
b
Poisson regression.