Table 7.

WOMAC function values following hyaluronic acid administration.

Study/Interval	Baseline		Follow-Up		p-value
	Mean	SD	Mean	SD
2-weeks
Berg et al. 200452	35.8	9.5	10.9	–	<0.05
1-month
Di Sante et al. 201636	57.65	26.2	47.69	21.2	>0.05
Atchia et al. 201150
Dıraçoğlu et al. 200939	6.23	0.78	4.57	0.63	<0.001
3-months
Eymard et al. 201753	84	–	58	–	<0.0001
Conrozier et al. 200642	50.8	20.3	34.4	26.9	–
Berg et al. 200452	35.8	9.5	15.9	–	<0.05
Conronzier et al. 200346	54.2	23.2	34.6	27.2	<0.001
4-months
Di Sante et al. 201636	57.65	26.2	32.91	20.6	<0.01
159 days (Range: 60–180)
Conrozier et al. 200926	89	57	67.4	8.3	0.019
6-months
Doria et al. 201735	28.5	2.5	11.3	4.5	–
26-weeks
Spitzer et al. 201051	64.42	1.40	–	–	<0.0001
12-months
Doria et al. 201735	28.5	2.5	10.9	4.2	–

WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index; SD: standard deviation.