Table 1.
Specific Pharmacological Inhibitors Have Helped Reveal the Intricacies of the Vector-Mediated Transduction Mechanisms
Name | Functions | References |
---|---|---|
Heparin | closely related in structure to membrane heparan sulfate | 34,35 |
Jasplakinolide | prevents actin depolymerization | 36 |
5-(N-ethyl-N-isopropyl) amiloride (EIPA) | inhibits CLIC/GEEC endocytosis as an inhibitor of Na+/H+ exchange of cytomembrane | 19,36 |
Bafilomycin A1 | a lysosome acidification inhibitor | 15 |
Brefeldin A | inhibits protein transport from the Golgi apparatus to the endoplasmic reticulum | 37,38 |
MG132 | prevents cellular proteasome-mediated degradation | 15 |