Table 5.
Multivariate Logistic Regression Models for Risk Factors of Severe Human Metapneumovirus (hMPV) Respiratory Tract Infection (RTI) or Respiratory Syncytial Virus (RSV) RTI Among Children in the Hospital or Clinic
| Adjusted OR (95% CI) |
||||
|---|---|---|---|---|
| Risk Factor | hMPV, Hospital vs Clinic | hMPV, Severe Disease, Hospital (Severity Score ≥1)a | RSV, Hospital vs Clinic | RSV, Severe Disease, Hospital (Severity Score ≥2)a |
| Age <6 mo | 2.66 (1.04–6.81) | … | 4.63 (2.94–7.28) | 2.26 (1.31–3.89) |
| Age <12 mo | … | 1.81 (0.51–6.45) | … | … |
| ≥3 children in the household | 2.86 (1.17–6.98) | … | 1.93 (1.24–3.00) | … |
| Prematurity (<37 wk GA) | 2.31 (0.73–7.30) | 13.97 (1.50–130.0) | 1.29 (0.68–2.43) | 3.08 (1.63–5.83) |
| Female sex | … | 4.32 (1.26–14.85) | … | … |
| Genotype B infection | … | 4.34 (1.27–14.88) | … | … |
| Presence of a comorbidity | … | … | 1.99 (1.00–3.93) | … |
| History of breast-feeding | … | … | 0.55 (0.33–0.92) | … |
| Viral coinfection | … | … | 0.48 (0.30–0.78) | 0.58 (0.25–1.35) |
Statistically significant ORs are in bold. Cells with ellipses denote that the associated variable was not retained in that model.
Abbreviations: CI, confidence interval; GA, gestational age; OR, odds ratio.
a Patients were attributed 1 point for the presence of each of the following criteria: admission to the pediatric intensive care unit, duration of hospitalization >5 days, requirement for supplemental oxygen therapy (fraction of inhaled O2 ≥ 0.3).