Table 1.
Some cell types established from bats and range of viruses that have been used in studies with these cells.
| Bat primary cells or cell lines | Origin | Virus/pseudovirus used in the study | Reference |
|---|---|---|---|
| Artibeus jamaicensis primary cells | Embryonic, primary kidney cells | Dengue virus, MERS-CoV | Moreira-Soto et al. (2017); Munster et al. (2016) |
| Carollia perspicillata. | Trachea | Vesicular stomatitis virus (VSV) and Rift-Valley fever virus | Eckerle et al. (2014) |
| Carollia perspicillata – CpKd | Kidney | Bat-associated influenza viruses | Hoffmann et al. (2016) |
| Eidolon helvum | Trachea | VSV and Rift-Valley fever virus | Eckerle et al. (2014) |
| Eidolon helvum – EidNi/41 | Kidney | Bat-associated influenza viruses, Ebolavirus, MERS-CoV, Influenza A virus, O'nyong–nyong virus | Hoffmann et al. (2016), Ng et al. (2015); Cai et al. (2014); Poole et al. (2014); Biesold et al. (2011) |
| Epomops buettikoferi – EpoNi/22.1 | Kidney | Bat-associated influenza viruses, Influenza A virus | Hoffmann et al. (2016); Poole et al. (2014) |
| Eptesicus fuscus – Efk3 | kidney | VSV, porcine epidemic diarrhea virus, herpes simplex virus and MERS-CoV | Banerjee et al. (2016) |
| Hypsignathus monstrosus – hypLu/45.1 | Lung | MERS-CoV, Influenza A virus | Cai et al. (2014); Poole et al. (2014) |
| Hypsignathus monstrosus – hypNi/1.1 | Kidney | Bat-associated influenza viruses, MERS-CoV, Influenza A virus, African Henipavirus | Hoffmann et al. (2016); Cai et al. (2014); Poole et al. (2014);. Kruger et al., (2013) |
| Miniopterus schreibersii primary cells | Lymph node (MsLn), Kidney (MsKi) | Miniopterus schreibersii herpesvirus (MsHV) | Zhang et al. (2012) |
| Myotis daubentonii – MyDauLu/47.1 | Lung | Influenza A virus | Poole et al. (2014) |
| Myotis davidii – MdKi | Kidney | Sendai virus | Liang et al. (2015) |
| Myotis myotis | brain (MmBr), tonsil (MmTo), peritoneal cavity (MmPca), nasal epithelium (MmNep) and nervus olfactorius (MmNol) | Rabies virus, European bat lyssavirus (EBLV – 1 and 2) | He et al. (2014) |
| Myotis velifer incautus (MVI-it) – CRL-6012 | intercapsular tumor | Novel bat gammaherpesvirus | Shabman et al. (2016); Host and Damania (2016) |
| Pipistrellus ceylonicus | Embryonic | Chandipura virus (CHPV), novel adenovirus (BtAdv-RLM) | Mourya et al. (2013) |
| Pipistrellus subflavus – ESU-BSL | Lung | MERS-CoV | Cai et al. (2014) |
| Pteropus alecto | Aorta, bone marrow, brain, foetus, foetal membranes, heart, kidney, liver, lymph nodes, lung, muscle, pharynx, placenta, salivary gland, small intestine, skin, spleen, testes, thymus, uterus | Hendra virus, Pulau virus, Sendai virus, Nipah virus, Hendra virus | Zhou et al. (2013); Crameri et al. (2009); Virtue et al. (2011) |
| Pteropus alecto | Kidney | Influenza A virus, Sendai virus, Pteropine orthoreovirus NB, Nipah virus, Hendra virus | Dlugolenski et al. (2013); Zhou et al. (2013); Virtue et al. (2011) |
| Pteropus alecto | Embryonic | Nipah virus, Hendra virus | Virtue et al. (2011) |
| Rhinolophus affinis | embryonic | VSV | Li et al., (2015) |
| Rhinolophus sinicus | splenocytes | VSV | Li et al., (2015) |
| Rousettus aegyptiacus – RO6E, RO5T | Kidney | MERS-CoV, Influenza A virus, Ebola virus, Marburg virus | Cai et al. (2014); Poole et al. (2014);. Krahling et al. (2010) |
| Rousettus aegyptiacus – RoNi/7.1 | Kidney | Bat-associated influenza viruses, MERS-CoV, Influenza A virus | Hoffmann et al. (2016); Cai et al. (2014); Poole et al. (2014) |
| Tadaria brasiliensis – Tb1Lu | Lung | Bovine leukemia virus, Influenza A virus, mammalian reovirus serotype 3 Dearing | Graves and Ferrer (1976); Poole et al. (2014);. Sandekian et al. (2013) |
| Rousettus aegyptiacus immortalized cells | Foetus | Vaccinia Ankara | Jordan et al. (2009) |