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. 2020 Mar 31;6(3):e03617. doi: 10.1016/j.heliyon.2020.e03617

Table 2.

Nutrition Impact Symptoms for interference score equal to 1 vs ≥ 2 for all treatment naïve head and neck cancer patients and by Eichner Index Class.

Nutrition Impact Symptom
Interference (n,%)
All Patients
Eichner Index (EI) Class
P-value
n = 104 A (n = 44) B (n = 47) C (n = 13)
No Chewing Difficulty 73 (70.2) 40 (90.9)a 27 (57.4)b 6 (46.2)b 0.000
Chewing Difficulty 31 (29.8) 4 (9.1) 20 (42.6) 7 (53.8)
No Dysphagia 70 (67.3) 36 (81.8)a 28 (59.6)ab 6 (46.2)b 0.016
Dysphagia 34 (32.7) 8 (18.2) 19 (40.4) 7 (53.8)
No Dry Mouth 90 (86.5) 42 (95.5)a 39 (83.0)ab 9 (69.2)b 0.023
Dry Mouth 14 (13.5) 2 (4.5) 8 (17.0) 4 (30.8)
No Thick Saliva 89 (85.6) 42 (95.5)a 38 (80.9)ab 9 (69.2)b 0.019
Thick Saliva 15 (14.4) 2 (4.5) 9 (19.1) 4 (30.8)
No Sore Mouth 80 (76.9) 40 (90.9)a 30 (63.8)b 10 (76.9)ab 0.007
Sore Mouth 24 (23.1) 4 (9.1) 17 (36.2) 3 (23.1)
No Pain 68 (65.4) 38 (86.4)a 24 (51.1)b 6 (46.2)b 0.000
Pain 36 (34.6) 6 (13.6) 23 (48.9) 7 (53.8)
No Loss of Appetite 77 (74.0) 38 (86.4)a 29 (61.7)b 10 (76.9)ab 0.023
Loss of Appetite 27 (26.0) 6 (13.6)b 18 (38.3)a 3 (23.1)
No Lack of Energy 82 (78.8) 43 (97.7)a 31 (66.0)b 8 (61.5)b 0.000
Lack of Energy 22 (21.2) 1 (2.3) 16 (34.0) 5 (38.5)
No Depression 86 (82.7) 41 (93.2)a 35 (74.5)b 10 (76.9)ab 0.036
Depression 18 (17.3) 3 (6.8) 12 (25.5) 3 (23.1)
No Feeling Full 87 (83.7) 41 (93.2)a 35 (74.5)b 11 (84.6)ab 0.043
Feeling Full 17 (16.3) 3 (6.8) 12 (25.5) 2 (15.4)
No Constipation 97 (93.3) 44 (100.0)a 41 (87.2)b 12 (92.3)ab 0.034
Constipation 7 (6.7) 0 (0) 6 (12.8) 1 (7.7)
No Anxiety 79 (76.0) 37 (84.1)a 32 (68.1)a 10 (76.9)a 0.198
Anxiety 25 (24.0) 7 (15.9) 15 (31.9) 3 (23.1)
No Diarrhea 99 (95.2) 44 (100.0)a 42 (89.4)a 13 (100.0)a 0.067
Diarrhea 5 (4.8) 0 (0) 5 (10.6) 0 (0)
No Nausea 92 (88.5) 41 (90.9)a 38 (80.9)a 13 (100.0)a 0.116
Nausea 12 (11.5) 4 (9.1) 9 (19.1) 0 (0)
No Smell Bothersome 101 (97.1) 44 (100.0)a 44 (93.6)a 13 (100.0)a 0.347
Smell Bothersome 3 (2.9) 0 (0) 3 (6.4) 0 (0)
No Vomiting 102 (98.1) 44 (100.0)a 45 (95.7)a 13 (100.0)a 0.614
Vomiting 2 (1.9) 0 (0) 2 (4.3) 0 (0)
No Other (lack of money, etc) 98 (94.2) 43 (97.7)a 43 (91.5)a 12 (92.3)a 0.396
Other (lack of money, etc) 6 (5.8) 1 (2.3) 4 (8.5) 1 (7.7)

Each subscript letter denotes a subset of the Eichner Index class whose column proportions significantly do not differ from each other at the 0.05 level.

Fisher's Exact test or Chi-square test applied (2-sided).