Table 2.
Acquiring cefoxitin resistance increased the spectrum of AMR in CNS to several classes of antimicrobials after controlling the effect of location and sample source as a random effect in the GLM model.
| Variables | No. of classes∗ of antimicrobials ineffective (Mean) | 95% CI | F | p-value | |
|---|---|---|---|---|---|
| Source | Abattoir | 3.5 | 2.8–4.3 | 6.726 | 0.054 |
| Dairy farm | 5.0 | 4.2–5.7 | |||
| Area | Assela | 2.8 | 1.4–4.1 | 2.237 | 0.227 |
| Adama | 3.4 | 2.1–4.6 | |||
| Holeta | 3.7 | 2.7–4.7 | |||
| Bishoftu | 4.3 | 3.4–5.2 | |||
| Addis Ababa | 5.2 | 4.1–6.3 | |||
| Cefoxitin | Cefoxitin-S | 2.6 | 1.9–3.4 | 21.990 | 0.007 |
| Cefoxitin-R | 5.1 | 4.4–5.8 |
∗
The 14 antimicrobials tested were regrouped into nine broad classes of antimicrobials. Table 2 showed the average number of ineffective antimicrobials of the nine antimicrobial classes tested against an individual CNS isolate from abattoir, dairy farm, five different locations, and by cefoxitin response status.