Table 2.
Laboratory test results and echocardiographic and angiographic characteristics
| Before PS match | P value | After PS match | P value | |||
|---|---|---|---|---|---|---|
| ACEI/ARB(-) | ACEI/ARB(+) | ACEI/ARB(-) | ACEI/ARB(+) | |||
| (n: 1300) | (n: 1201) | (n: 1050) | (n: 1050) | |||
| Laboratory values | ||||||
| WBC, X109/L | 6.8 (5.6, 8.7) | 6.6 (5.5, 8.1) | <0.05 | 8.4 (6.3, 10.1) | 7.9 (6.1, 10.2) | NS |
| Neutrophil, X109/L | 4.5 (3.6, 5.9) | 4.4 (3.5, 5.5) | <0.05 | 5.9 (4.3, 7.7) | 5.5 (4.0, 7.7) | NS |
| Monocyte, X109/L | 0.29 (0.16, 0.44) | 0.27 (0.16, 0.41) | NS | 0.27 (0.15, 0.42) | 0.28 (0.16, 0.41) | NS |
| Hemoglobin, g/L | 134.5 ± 16.5 | 133.7 ± 15.7 | <0.05 | 133.0 ± 18.9 | 132.9 ± 19.1 | NS |
| Hs-CRP, mg/L | 2.7 (1.0, 10.4) | 2.0 (0.8, 5.4) | <0.001 | 10.5 (2.9, 23.3) | 6.1 (2.0, 16.7) | <0.05 |
| FBG, mmol/L | 7.0 (5.8, 9.0) | 6.8 (5.7, 8.3) | <0.05 | 7.5 (6.2, 9.3) | 7.5 (6.3, 10.2) | NS |
| RBG at admission, mmol/L | 9.9 (7.5, 13.3) | 9.7 (7.2, 12.8) | <0.05 | 10.8 (8.1, 14.6) | 11.0 (8.7, 14.2) | NS |
| Glycated hemoglobin, % | 7.5 ± 1.5 | 7.5 ± 1.6 | NS | 7.7 ± 1.7 | 7.8 ± 1.7 | NS |
| ALT, U/L | 19.0 (13.0, 28.0) | 18.0 (13.0, 27.0) | NS | 22.0 (15.0, 39.0) | 21.0 (14.0, 35.0) | NS |
| Creatinine, µmol/L | 76.0 (65.3, 88.1) | 77.8 (66.2, 90.6) | <0.05 | 81.8 (70.6, 96.9) | 81.0 (68.7, 94.0) | NS |
| eGFR, ml/min/1.73 m2 | 84.9 (71.4, 97.9) | 82.3 (67.9, 95.3) | <0.001 | 79.1 (64.5, 94.5) | 79.2 (64.0, 95.2) | NS |
| TC, mmol/L | 4.3 (3.6, 5.0) | 4.2 (3.4, 4.9) | NS | 4.45 ± 0.97 | 4.48 ± 1.12 | NS |
| TG, mmol/L | 1.5 (1.1, 2.2) | 1.5 (1.1, 2.1) | NS | 1.5 (1.1, 2.0) | 1.7 (1.2, 2.3) | NS |
| LDL-C, mmol/L | 2.4 (1.9, 2.9) | 2.3 (1.8, 2.8) | < 0.001 | 2.6 (2.1, 3.1) | 2.6 (2.0, 3.1) | NS |
| HDL-C, mmol/L | 1.0 (0.9, 1.2) | 1.0 (0.9, 1.2) | NS | 1.0 (0.9, 1.2) | 1.0 (0.8, 1.2) | NS |
| NT-Pro BNP,pg/ml | 1621(644, 4214) | 1585(521, 4548) | NS | 1855(657, 4571) | 1585(487, 4357) | NS |
| Echocardiographic values | ||||||
| LVEDD, cm | 5.06 ± 0.49 | 5.04 ± 0.48 | NS | 5.13 ± 0.51 | 5.17 ± 0.52 | NS |
| LVESD, cm | 3.28 ± 0.57 | 3.21 ± 0.51 | <0.05 | 3.53 ± 0.59 | 3.51 ± 0.61 | <0.05 |
| LVEF, % | 63.93 ± 8.92 | 65.66 ± 7.51 | <0.001 | 58.5 ± 9.4 | 60.0 ± 9.7 | <0.05 |
| LVFS, % | 35.33 ± 6.22 | 36.52 ± 5.92 | <0.001 | 31.4 ± 6.2 | 32.8 ± 7.2 | <0.05 |
| LVEDV, ml | 122.9 ± 28.3 | 122.2 ± 27.9 | NS | 127.5 ± 30.0 | 129.9 ± 31.9 | NS |
| LVESV, ml | 41.0 (32.2, 51.2) | 38.2 (32.2, 48.4) | <0.05 | 47.4 (38.8, 65.9) | 47.4 (36.7, 62.0) | NS |
| LA,cm | 3.71 ± 0.43 | 3.74 ± 0.41 | <0.05 | 3.76 ± 0.45 | 3.78 ± 0.42 | NS |
| E/A | 0.80 (0.68, 1.00) | 0.79 (0.68, 1.00) | NS | 0.84 (0.69, 1.16) | 0.81 (0.67, 1.16) | NS |
| SV, ml | 76.7 (66.5, 87.9) | 79.2 (68.7, 88.9) | <0.05 | 70.8 (63.4, 83.7) | 75.4 (65.4, 87.1) | NS |
| Angiography values | ||||||
| Involved vessel | ||||||
| Single vessel | 180 (13.8) | 158 (13.2) | NS | 157 (15.0) | 138 (13.1) | NS |
| Multi-vessel/LM | 1120 (86.2) | 1043 (86.8) | 893 (85.0) | 912 (86.9) | ||
| CTO | 122 (9.4) | 108 (9.0) | NS | 92 (8.8) | 88 (8.4) | NS |
| Proximal LAD | 697 (53.6) | 626 (52.1) | NS | 557 (53.0) | 551 (52.5) | NS |
Data are presented as mean ± SD, IQR or n (%)
WBC white blood cell count, Hs-CRP high sensitivity C reactive protein, FBG fasting blood glucose, RBG random blood glucose, ALT alanine transaminase, eGFR estimated glomerular filtration rate, TC total cholesterol, TG triglycerides; LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, NT-Pro BNP N-terminal pro-brain natriuretic peptide, LVEDD left ventricular end-diastolic diameter, LVESD left ventricular end-systolic diameter, LVEF left ventricular ejection fraction, LVFS left ventricular fraction shortening, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LA left atrium, E/A ratio of early to late ventricular filling velocities, SV stroke volume, LM left main coronary artery, CTO chronic total occlusions, LAD left anterior descending, NS non-significant