Table 4.
Clinical events during long-term follow-up
| ACEI/ARB(-) | ACEI/ARB(+) | HR(95%CI) | P value | |
|---|---|---|---|---|
| Overall population | ||||
| Number | 1300 | 1201 | ||
| Composite MACCE | 373 (28.7) | 277 (23.1) | 1.23 (1.06,1.44) | <0.05 |
| All cause death | 59 (4.5) | 57 (4.7) | 0.92 (0.64,1.32) | NS |
| CV death | 49 (3.8) | 37 (3.1) | 1.18 (0.77,1.81) | NS |
| Non-fatal MI | 57 (4.4) | 37 (3.1) | 1.38 (0.91,2.08) | NS |
| Non-fatal stroke | 52 (4.0) | 29 (2.4) | 1.62 (1.03,2.56) | <0.05 |
| Revascularization | 102 (7.8) | 92 (7.7) | 0.98 (0.74,1.29) | NS |
| Cardiac rehospitalization | 290 (22.3) | 233 (19.4) | 1.12 (0.94, 1.33) | NS |
| Matched population | ||||
| Number | 1050 | 1050 | ||
| Composite MACCE | 312 (29.7) | 242 (23.1) | 1.21 (1.02, 1.43) | <0.05 |
| All cause death | 53 (5.0) | 51 (4.9) | 0.95 (0.65, 1.40) | NS |
| CV death | 44 (4.2) | 33 (3.1) | 1.24 (0.79, 1.94) | NS |
| Non-fatal MI | 48 (4.6) | 31 (3.0) | 1.45 (0.92, 2.28) | NS |
| Non-fatal stroke | 48 (4.6) | 25 (2.4) | 1.82 (1.13, 2.96) | <0.05 |
| Revascularization | 76 (7.2) | 81 (7.7) | 0.85 (0.62, 1.16) | NS |
| Cardiac rehospitalization | 241 (23.0) | 202 (19.2) | 1.09 (0.91, 1.32) | NS |
ACEI/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, MACCE major adverse cardiac and cerebral event, CV cardiovascular, MI myocardial infarction, HR hazard ratio, CI confidence interval, NS non-significant