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. 2020 Apr 1;18:150. doi: 10.1186/s12967-020-02314-y

Table 5.

Multivariate COX regression analysis of non-fatal stroke

Univariate Multivariate
HR (95%CI) P value Adjusted HR (95%CI) P value
Age, y 1.02 (0.99, 1.05) NS 0.99 (0.97, 1.02) NS
ACEI/ARB(-) 1.82 (1.13, 2.96) < 0.05 1.72 (1.05, 2.84) < 0.05
Beta-blocker before admission 0.54 (0.29, 1.01) NS 0.56 (0.30, 1.06) NS
Previous stroke 4.00 (2.52, 6.35) < 0.001 3.70 (2.29, 5.96) < 0.001
Hemoglobin, g/L 0.98 (0.96, 0.99) < 0.05 0.99 (0.97, 1.01) NS
AMI at admission 2.10 (1.32, 3.35) < 0.05 1.07 (0.61, 1.86) NS
LVEF, % 0.95 (0.93, 0.97) < 0.001 0.96 (0.94, 0.99) < 0.05
Involved vessel 1.79 (1.28, 2.49) < 0.05 1.52 (1.08, 2.14) < 0.05
In-hospital treatment
 ACEI/ARB 0.72 (0.46, 1.14) NS 0.85 (0.52, 1.38) NS
 Antiplatelet agents 0.34 (0.16, 0.75) <0.05 0.49 (0.19, 1.25) NS
 Statins 0.43 (0.24, 0.76) <0.05 0.58 (0.30, 1.11) NS

ACEI/ARB(-) no Angiotensin-converting enzyme inhibitor/Angiotensin receptor blocker therapy before admission, AMI acute myocardial infarction, LVEF left ventricular ejection fraction; NS Non-significant