Table 6.
Multivariate COX regression analysis of composite MACCE
| Univariate | Multivariate | |||
|---|---|---|---|---|
| HR(95%CI) | P value | Adjusted HR(95%CI) | P value | |
| Age,y | 1.01 (0.99, 1.02) | NS | 1.00 (0.99, 1.01) | NS |
| Male, % | 1.05 (0.89, 1.25) | NS | 1.05 (0.82, 1.33) | NS |
| ACEI/ARB(-) | 1.21 (1.02, 1.43) | < 0.05 | 1.24 (1.04, 1.48) | < 0.05 |
| Previous stroke | 1.57 (1.29, 1.90) | < 0.001 | 1.49 (1.22, 1.82) | < 0.001 |
| Smoking | 1.09 (0.93, 1.29) | NS | 1.05 (0.85, 1.31) | NS |
| Hemoglobin, g/L | 1.00 (0.99, 1.00) | NS | 0.99 (0.98, 1.00) | NS |
| Glycated hemoglobin, % | 1.08 (1.02, 1.14) | < 0.05 | 1.05 (0.99, 1.11) | NS |
| LDL-C, mmol/L | 1.15 (1.03, 1.28) | < 0.05 | 1.07 (0.95, 1.20) | NS |
| eGFR ml/min/1.73 m2 | 0.98 (0.97, 0.99) | < 0.001 | 0.98 (0.97, 0.99) | < 0.05 |
| AMI at admission | 1.62 (1.36, 1.93) | < 0.001 | 1.18 (0.96, 1.45) | NS |
| LVEF, % | 0.97 (0.96, 0.98) | < 0.001 | 0.98 (0.97, 0.99) | < 0.001 |
| Involved vessel | 1.45 (1.29, 1.62) | < 0.001 | 1.34 (1.19, 1.51) | <0.001 |
| CTO | 1.49 (1.23, 1.81) | < 0.001 | 1.07 (0.87, 1.33) | NS |
| In-hospital treatment | ||||
| Antiplatelet agents | 0.45 (0.33, 0.63) | < 0.001 | 0.45 (0.31, 0.65) | < 0.001 |
| ACEI/ARB | 0.92 (0.78, 1.09) | NS | 1.00 (0.84, 1.19) | NS |
| Beta-blocker | 0.93 (0.78, 1.12) | NS | 0.87 (0.72, 1.06) | NS |
| Statins | 0.75 (0.58, 0.95) | <0.05 | 0.94 (0.72, 1.23) | NS |
ACEI/ARB(-) no angiotensin-converting enzyme inhibitor/angiotensin receptor blocker therapy before admission, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, AMI acute myocardial infarction, LVEF left ventricular ejection fraction, CTO chronic total occlusions; NS non-significant