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. 2006 Mar 24;36(3):607–640. doi: 10.1016/j.cvsm.2005.12.003

Table 2.

Canine pediatric vaccines: core, noncore, and generally not recommended

Canine Core Noncore Not recommended
CDV MLV or recombinant beginning at 6–9 weeks, given every 3–4 weeks until ∼16 weeks of age
CAV II MLV, frequency as for CDV
Parvovirus MLV, frequency as for CDV
Rabies Killed, single dose, minimum age dependent on state and local regulations (12 or 16 weeks)
Leptospirosis Killed bacterin or purified subunit product beginning at 12 weeks, 2 to 3 doses given at 4- week intervals
Bordetella bronchiseptica Attenuated bacterin, a single dose of an intranasal vaccine given 1 week before potential exposure (minimum of 4 weeks of age)
Parainfluenza MLV, either use topical product combined with B bronchiseptica or parenteral vaccine contained in multivalent DAPP products
Lyme disease (Borrelia burgdorferi) Recombinant subunit vaccine (OspA) before exposure to ticks, 2 doses given 4 weeks apart beginning at 9 weeks of age
Measles No longer recommended, use recombinant distemper vaccine for high-risk puppies instead of measles
Coronavirus Not recommended
Giardia lamblia Not recommended
Rattlesnake vaccine Insufficient data to evaluate efficacy; prevention of exposure, aversion training, and immediate veterinary attention after exposure highly recommended
CAV I Not recommended; CAV II to prevent CAV I infection is highly recommended

Abbreviations: CAV, canine adenovirus; CDV, canine distemper virus; DAPP, distemper, parvovirus, and parainfluenza; MLV, modified-live virus; OspA, outer surface protein A