Table 2.
Prediction of the putative pp1ab cleavage sites.
| NSP | BatCoV-ITA3 | BatCoV-ITA4 | BatCoV-ITA5 | Putative functional domain(s)a |
|---|---|---|---|---|
| NSP1 | M1-A107 | M1-G107 | M1-G107 | |
| NSP2 | G108-G771 | G108-G771 | G108-G771 | |
| NSP3 | G772-G2361 | G772-G2374 | G772-G2389 | ADRP, PL2pro |
| NSP4 | G2362-Q2838 | G2375-Q2851 | G2390-Q2866 | |
| NSP5 | A2839-Q3140 | A2852-Q3153 | A2867-Q3168 | 3CLpro |
| NSP6 | S3141-Q3419 | S3154-Q3432 | S3169-Q3447 | |
| NSP7 | S3420-Q3502 | S3433-Q3515 | S3448-Q3530 | |
| NSP8 | S3503-Q3697 | S3516−Q3710 | S3531-Q3725 | Primase |
| NSP9 | N3698-Q3805 | N3711-Q3818 | N3726-Q3833 | |
| NSP10 | A3806-Q3940 | A3819-Q3953 | A3834-Q3968 | |
| NSP11 | T3941-L3958 | T3954-L3971 | T3969-L3986 | Short peptide at the end of ORF1a |
| NSP12 | T3941-Q4867 | T3959-Q4880 | T3964-Q4895 | RdRp |
| NSP13 | S4868-Q5464 | A4881-Q5477 | A4896-Q5492 | HEL, NTPase |
| NSP14 | A5465-Q5982 | A5478-Q5995 | A5493-Q6010 | ExoN, NMT |
| NSP15 | S5983-Q6321 | S5996-Q6330 | S6011-Q6348 | NendoU |
| NSP16 | S6322-V6623 | S6331-K6631 | S6349-V6646 | OMT |
a
ADRP ADP-ribose 1-phosphatase, PL2pro papain-like protease 2, 3CLpro coronavirus NSP5 protease, Hel helicase, NTPase nucleoside triphosphatase, ExoN exoribonuclease, NMT N7 methyltransferase, NendoU endoribonuclease, OMT 2′ O-methyltransferase.