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. 2020 Mar 17;5(12):6967–6982. doi: 10.1021/acsomega.0c00327

Scheme 2. General Synthetic Route for the 2-Amino Benzimidazole Analogues (43).

Scheme 2

Reaction and conditions: (a) R5-CHO, Na(OAc)3BH, AcOH, DCM, 20–27 °C, 2–24 h (16–49%).