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. 2009 Jun 12;39(3):395–418. doi: 10.1016/j.cvsm.2009.02.003

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Copyright © 2009 Elsevier Inc. All rights reserved.

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Fig. 17 — Copper-related chronic hepatitis in a dog. In this liver, the aggregates of macrophages contain granular pigment, typical of copper, with an abundance of mononuclear inflammatory cells within the lesion. Surrounding hepatocytes also contain fine granular pigment as a result of copper retention.