Table II.
Characteristics in patients without early gastric cancer, with or without H. pylori infection.
| Characteristic | H. pylori-negative (n=5) | H. pylori-positive (n=15) | P-value |
|---|---|---|---|
| Sex, n (n; %)a | NS | ||
| Male | 2 (0; 0.0) | 10 (0; 0.0) | |
| Female | 3 (0; 0.0) | 5 (2; 40.0) | |
| Mean age ± SEM (range), years | 66.8±2.3 (62–74) | 58.1±3.9 (30–81) | NS |
| <65 years, n (n; %)a | 2 (0; 0.0%) | 8 (0; 0.0) | NS |
| ≥65 years, n (n; %)a | 3 (0; 0%) | 7 (2; 28.6) | |
| Gastric atrophy, years, n (n; %)a | <0.0001 | ||
| None | 5 (0; 0.0) | 0 (0; 0.0) | |
| Closed | 0 (0; 0.0) | 7 (1; 14.3) | |
| Open | 0 (0; 0.0) | 8 (1; 12.5) | |
| SOCS3 methylation positive | 0 (0.0) | 2 (13.3) | NS |
a
The number of patients positive for SOCS3 methylation and the percentage. GC, gastric cancer; NS, not significant; H. pylori, Helicobacter pylori; SOCS3, suppressor of cytokine signaling 3; SEM, standard error of the mean.