Table III.
Characteristics in patients with early gastric cancer with H. pylori infection and patients with early gastric cancer without H. pylori infection.
| Characteristics | Without early GC H. pylori-positive, n=15 | With early GC, n=51 | P-value, with vs. without |
|---|---|---|---|
| Sex, n (n; %)a | NS | ||
| Male | 10 (0; 0.0%) | 39 (12; 30.8) | |
| Female | 5 (2; 40.0%) | 12 (5; 41.7) | |
| Mean age ± SEM (range), years | 58.1±3.9 (30–81) | 71.1±1.2 (48–87) | 0.0002 |
| <65 years, n (n; %)a | 8 (0; 0.0) | 13 (4; 30.8) | 0.047b |
| ≥65 years, n (n; %)a | 7 (2; 28.6) | 38 (13; 34.2) | |
| Gastric atrophy, n (n; %)a | 0.0002b | ||
| None | 0 (0; 0.0) | 0 (0; 0.0) | |
| Closed | 7 (1; 14.3) | 10 (4; 40.0) | |
| Open | 8 (1; 12.5) | 41 (13; 31.7) | |
| SOCS3 methylation positive | 2 (13.3) | 17 (33.3) | 0.046b |
a
The number of patients positive for SOCS3 methylation and the percentage.
b
P-value analyzed by χ2 test. GC, gastric cancer; NS, not significant; H. pylori, Helicobacter pylori; SOCS3, suppressor of cytokine signaling 3; SEM, standard error of the mean.