Figure 1.
Relative miR-665 expression measured by reverse transcription-quantitative PCR. (A) Relative expression of miR-665 in NSCLC tissues (n=128) was significantly higher compared with that in the normal controls (n=128). (B) Relative expression of miR-665 in patients with positive LM (n=66) was significantly higher than in those with negative LM (n=62). (C) Relative expression of miR-665 was significantly higher in patients with advanced TNM stage (n=67) compared with in patients with early TNM stage (n=61). (D) Relative miR-665 expression was higher in the three NSCLC cell lines (A549, H1299, H522) compared with normal 16HBE cells. **P<0.01, ***P<0.001. NSCLC, non-small cell lung cancer; LM, lymph node metastasis; miR-665, miRNA-665.