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PTPRB serves as a direct target of miR-665 in H1299 cells. (A) Complementary sequence of miR-665 in the 3′-UTR of PTPRB. (B) Overexpression of miR-665 inhibited the luciferase activity, while the knockdown of miR-665 promoted the luciferase activity in cells transfected with the WT 3′-UTR of PTPRB. *P<0.05, **P<0.01 vs. control. UTR, untranslated region; PTPRB, protein tyrosine phosphatase receptor type B; NC, negative control; miR-665, miRNA-665; WT, wild-type; MT, mutant.
