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Pathway network associated with PCOS. Five genes (LEP, SPP1, F2R, IL12B and RBP4) and two important pathways (the Jak-STAT signaling pathway and neuroactive ligand-receptor interaction) were involved in this pathway network. PCOS, polycystic ovarian syndrome; LEP, leptin; SPP1, secreted phosphoprotein 1; F2R, coagulation factor 2 receptor; IL12B, interleukin-12 subunit β; RBP4, retinol binding protein 4; KEGG, Kyoto Encyclopedia of Genes and Genomes.
