Table IV.
Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis for the genes in the PPI network.
| Term | Count | P-value | Genes |
|---|---|---|---|
| hsa05200: Pathways in cancer | 8 | 1.631×10−3 | CDKN1A, CTBP1, HSP90B1, ERBB2, PML, FGF13, FZD3, ZBTB16 |
| hsa04010: MAPK signaling pathway | 7 | 1.906×10−3 | MAP3K7, RPS6KA5, RPS6KA6, MKNK2, FGF13, RKACB, GADD45A |
| hsa00230: Purine metabolism | 5 | 2.757×10−3 | POLR2J, PNPT1, PDE5A, PDE4D, POLR2D |
| hsa04621: NOD-like receptor signaling pathway | 3 | 5.778×10−3 | MAP3K7, HSP90B1, TNFAIP3 |
| hsa04115: p53 signaling pathway | 3 | 6.723×10−3 | CDKN1A, GADD45A, TP73 |
| hsa04120: Ubiquitin mediated proteolysis | 4 | 6.914×10−3 | PRPF19, UBE2D4, UBE2A, PML |
| hsa04310: Wnt signaling pathway | 4 | 8.490×10−3 | MAP3K7, CTBP1, FZD3, PRKACB |
| hsa04540: Gap junction | 3 | 1.024×10−2 | TUBA8, TUBA4A, PRKACB |
| hsa04020: Calcium signaling pathway | 4 | 1.153×10−2 | ERBB2, PRKACB, MYLK, F2R |
| hsa04080: Neuroactive ligand-receptor interaction | 3 | 3.522×10−2 | LEP, S1PR3, F2R |
| hsa04630: Jak-STAT signaling pathway | 2 | 3.876×10-2 | LEP, IL12B |