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. 2020 Mar 13;21(5):2095–2102. doi: 10.3892/mmr.2020.11026

Table II.

APP and Beclin-1 mRNA levels in the hippocampus by reverse transcription-quantitative PCR.

Groupa APP Beclin-1
Normal 1.00±0.00 1.00±0.00
Model 4.21±0.11c 3.81±0.09c
Low-dose β-asarone 1.42±0.04b,e,f,h 1.39±0.03b,e,g,h
Medium-dose β-asarone 1.77±0.07c,e,g,h 1.64±0.05b,e,g,h
High-dose β-asarone 2.06±0.08c,e,g,h 1.86±0.06c,e,g,h
3-MA 1.25±0.05b,e 1.15±0.03b,e
Rapamycin 2.82±0.13c,e,g 3.07±0.11c,d,g
a

n=7 mice/group

b

P<0.05

c

P<0.01 vs. normal group

d

P<0.05

e

P<0.01 vs. model group

f

P<0.05

g

P<0.01 vs. 3-MA treated group

h

P<0.01 vs. rapamycin treated group. 3-MA, 3-methyladenine; APP, amyloid precursor protein.