Table II.
Groupa | APP | Beclin-1 |
---|---|---|
Normal | 1.00±0.00 | 1.00±0.00 |
Model | 4.21±0.11c | 3.81±0.09c |
Low-dose β-asarone | 1.42±0.04b,e,f,h | 1.39±0.03b,e,g,h |
Medium-dose β-asarone | 1.77±0.07c,e,g,h | 1.64±0.05b,e,g,h |
High-dose β-asarone | 2.06±0.08c,e,g,h | 1.86±0.06c,e,g,h |
3-MA | 1.25±0.05b,e | 1.15±0.03b,e |
Rapamycin | 2.82±0.13c,e,g | 3.07±0.11c,d,g |
n=7 mice/group
P<0.05
P<0.01 vs. normal group
P<0.05
P<0.01 vs. model group
P<0.05
P<0.01 vs. 3-MA treated group
P<0.01 vs. rapamycin treated group. 3-MA, 3-methyladenine; APP, amyloid precursor protein.