Table II.
Gene Ontology functional annotation of composite networks for BRS3 and UCP1.
| Function | Genes in network | Gene symbol | Fold change discovery |
|---|---|---|---|
| Fat cell differentiation | 2 | PPARD | 0.0007 |
| PPARG | 0.0005 | ||
| Sequestering of triglyceride | 1 | CIDEA | 0.0007 |
| PPARG | 0.0005 | ||
| Proton transport | 2 | UCP2 | 0.0049 |
| UCP3 | 0.0035 | ||
| Organelle inner membrane | 3 | UCP2 | 0.0049 |
| UCP3 | 0.0035 | ||
| SLC25A11 | 0.0014 | ||
| Hydrogen transport | 2 | UCP2 | 0.0049 |
| UCP3 | 0.0035 | ||
| Mitochondrial membrane | 4 | UCP2 | 0.0049 |
| UCP3 | 0.0035 | ||
| SLC25A11 | 0.0014 | ||
| TOMM20 | 0.0011 | ||
| Mitochondrial inner membrane | 3 | UCP2 | 0.0049 |
| UCP3 | 0.0035 | ||
| SLC25A11 | 0.0014 | ||
| Regulation of sequestering of triglyceride | 1 | CIDEA | 0.0007 |
| PPARG | 0.0005 | ||
| Electron transport chain | 2 | UCP2 | 0.0049 |
| UCP3 | 0.0035 | ||
| Fatty acid binding | 1 | PPARD | 0.0007 |
| PPARG | 0.0005 |
GRPR, GSTM1, GPX5, SRD5A2, DMD, CST3, C8G, CRISP1, DSC1, ASIP, UROS, COMP and WNT8B have not yet been ascertained in the composite network. BRS3, bombesin-like receptor 3; UCP, uncoupling protein; PPAR, peroxisome proliferator-activated receptor; SLC25A11, mitochondrial 2-oxoglutarate/malate carrier protein.