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. 2020 Mar 5;21(5):2041–2050. doi: 10.3892/mmr.2020.11013

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Copyright: © Yi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Nuclear localization of ATF6 in INS-1 cells after PA treatment. ATF6 was visualized in red, DAPI nuclear staining in blue. ATF6 (white arrows) localized to the cytoplasm of INS-1 cells in the control group, with no ATF6 expression in the nucleus. Treatment with 0.5 mM PA induced nuclear localization of ATF6 in INS-1 cells; ATF6 was expressed in both the cytoplasm and the nucleus (blank arrows). Magnification, ×40. ATF6, activating transcription factor 6; PA, palmitate.