Table 5.

Skin irritation testing: erythema and edema irritation scores of individual rabbits after 4-hour substance exposure

Test substance	Animal no.	Primary Irritation Index (PII) score (erythema/edema)*								Final PII‡
		1 hour†		24 hours		48 hours		72 hours
		Test site 1	Test site 2	Test site 1	Test site 2	Test site 1	Test site 2	Test site 1	Test site 2
0.5% sodium hypochlorite	60135	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
	60136	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0.0
	60137	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
0.5% sodium hypochlorite + color additive	60073	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
	60074	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0.0
	60075	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
0.5% calcium hypochlorite	60615	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
	60616	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0.1
	60617	0/0	0/0	0/0	0/0	0/0	0/0	2/0	0/0
0.5% calcium hypochlorite + color additive	60612	1/0	1/0	1/0	1/0	1/0	1/0	0/0	0/0
	60613	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0.2
	60614	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
0.5% NaDCC	60702	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
	60704	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0.0
	60706	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
0.5% NaDCC +  color additive	60696	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0
	60698	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0.0
	60700	0/0	0/0	0/0	0/0	0/0	0/0	0/0	0/0

NaDCC = sodium dichloroisocyanurate.

^*All readings were taken after the dressing removal.

^†1-hour scores are not included in determining PII.

^‡PII = sum of (erythema + edema scores) / (2 test sites x 3 observation points) for each animal / 3 animals.