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. 2020 Feb 20;56(5):1129–1139. doi: 10.3892/ijo.2020.4997

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Copyright: © Xue et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Forskolin induces EMT of CC cells in vitro. (A and C) Forskolin induced the morphological changes of JAR and JEG-3 cells from cobblestone-like to spindle-like. (B) Western blot and RT-qPCR was used to show the expression of EMT markers in forskolin-treated JAR cells. (D) Western blot and RT-qPCR was used to show the expression of EMT markers in forskolin-treated JEG-3 cells. ^*P<0.05, ^**P<0.01. CC, choriocarcinoma; EMT, epithelial-to-mesenchymal transition; RT-qPCR, reverse transcription-quantitative PCR.