Table 1.
Distribution of frequency of SNPs in MASP-2 genotyping among HCV patients
| Allele | SNP ID | mRNA | Genotype | HCV patients (%) | Controls (%) | p Valuea |
|---|---|---|---|---|---|---|
| p. R99Q | rs61735600 | c.296 G > A | GG | 103 (99.04) | 104 (100.00) | 1.0 |
| GA | 1 (0.96) | 0 (0.00) | ||||
| AA | 0 (0.00) | 0 (0.00) | ||||
| AA + GA | 1 (0.96) | 0 (0.00) | ||||
| p.D120G | rs72550870 | c.359 A > G | GG | 0 (0.00) | 0 (0.00) | 1.0 |
| GA | 2 (1.92) | 2 (1.92) | ||||
| AA | 102 (98.08) | 102 (98.08) | ||||
| GG + AG | 2 (1.92) | 2 (1.92) | ||||
| p. P126L | rs56392418 | c.377 C > T | CC | 103 (99.04) | 101 (97.12) | 0.621 |
| CT | 1 (0.96) | 3 (2.88) | ||||
| TT | 0 (0.00) | 0 (0.00) | ||||
| TT + CT | 1 (0.96) | 3 (2.88) | ||||
| p.D371Y | rs12711521 | c.1111 G > T | GG | 16 (15.53) | 4 (3.92) | 0.008 |
| GT | 35 (33.98) | 47 (46.08) | ||||
| TT | 52 (50.49) | 51 (50.00) | ||||
| TT + GT | 87 (84.47) | 98 (96.08) | ||||
| p. V377A | rs2273346 | c.1130 T > C | TT | 97 (94.17) | 93 (91.18) | 0.436 |
| TC | 6 (5.83) | 8 (7.84) | ||||
| CC | 0 (0.00) | 1 (0.98) | ||||
| CC + TC | 6 (5.83) | 9 (8.82) |
a
For p values, the results of the better genetic models are reported when the codominant and dominant models were tested by means of univariated analysis using the Fisher's exact test and χ2 test (p < 0.05).