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. 2006 May 11;24(26):5498–5508. doi: 10.1016/j.vaccine.2006.04.054

Table 1.

Reactivity of novel anti-RBD mAbs with S proteins in ELISAa

mAb Isotype Antigen
RBD-FC S1-Fc EC-S FL-S
S6 IgG1/k 2.89 1.18 2.06 2.53
S9 IgG1/k 2.25 1.33 2.07 2.28
S20 IgG1/k 2.92 2.23 2.49 2.58
S25 IgG1/k 2.82 1.97 2.27 2.46
S29 IgG2b/k 2.50 0.87 0.40 1.62
S33 IgG2b/k 2.55 0.87 0.58 1.81
S37 IgG1/k 2.84 1.28 2.19 2.40
S38 IgG1/k 2.60 2.12 2.48 2.44
S40 IgG1/k 2.85 1.97 2.59 2.62
S44 IgG1/k 2.85 2.63 2.42 2.50
S50 IgG1/k 2.85 1.48 2.13 2.55
S53 IgG2b/k 2.39 1.20 1.48 2.08
102D7b IgG1/k 0.01 0.01 2.00 2.75
a

Antigens were coated to ELISA plates at 0.5 μg/ml and mAbs were tested at 10 μg/ml. OD450 value >0.2 was considered positive reaction and highlighted in boldface.

b

102D7 is a control mAb targeting the S2 domain.