Skip to main content
. 2006 May 11;24(26):5498–5508. doi: 10.1016/j.vaccine.2006.04.054

Table 2.

Mapping of anti-RBD mAbs by binding competition assaysa

Group Competing mAb % Inhibition of binding by biotinylated mAb
S6 S20 S37 S38
A S6 92.22 13.41 94.71 -1.52
S9 95.78 19.47 97.55 8.05
S37 98.71 7.97 95.47 11.11
S40 99.77 19.83 99.58 10.13
S50 99.52 23.48 99.28 17.14



B S20 27.78 99.77 24.47 98.96
S38 27.45 98.92 24.85 99.20
S53 28.64 68.23 32.24 62.78



C S44 63.31 52.70 56.94 16.85



D S25 95.06 83.29 93.56 85.78



E S29 17.88 11.96 16.15 6.84
S33 13.07 11.64 24.47 10.19
a

Competing mAbs were tested at 100 μg/ml for the ability to block binding of the biotinylated mAbs to the RBD-Fc in ELISA. Greater than 40% inhibition was considered positive competition (values in bold). Negative numbers indicate increased binding of the biotinylated reagent.