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In vitro antiplasmodial activities of 8–22 against CQ-sensitive P. falciparum strain (D10) and CQ-resistant strains (Dd2 and K1), respectively. The IC50 values have been taken in reference to the values of CQ and FQ. The IC50 values in 
and 
indicate compounds with activities higher than FQ and CQ, respectively. On the other hand, the values in 
indicate compounds with activities higher than both CQ and FQ.
