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. 2009 Sep 2;27(48):6777–6790. doi: 10.1016/j.vaccine.2009.08.056

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Copyright © 2009 Elsevier Ltd. All rights reserved.

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Fig. 2 — Comparison of neutralization activity of immune sera against four different pseudotypes: H5HA (A/Thailand/1(KAN-1)/04, clade 1) and N1NA, H5HA (A/Shenzhen/406H/06, clade 2.3) and N1NA, H1HA (cleavage mutant of WSN) and N1NA and VSV-G control measured by PNA. (a) Immune serum elicited with priming of DNA expressing subclade 2.3 H5HA (A/Shenzhen/406H/06) and boosting of LVLP expressing both subclade 2.3 H5HA (A/Shenzhen/406H/06) and N1NA. (b) Immune serum elicited with priming of DNA expressing clade 1 H5HA (A/Thailand/1(KAN-1)/04) and boosting of LVLP expressing both clade 1 H5HA (A/Thailand/1(KAN-1)/04) and N1NA. (c) Immune serum elicited with priming and boosting of DNA expressing subclade 2.3 H5HA (A/Shenzhen/406H/06). (d) Immune serum elicited with priming and boosting of DNA expressing clade 1 H5HA (A/Thailand/1(KAN-1)/04).