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. 2018 Oct 23;161:456–467. doi: 10.1016/j.ejmech.2018.10.052

Table 2.

IC50 of 5-FU in the presence of 7a and 7b with HCT116 and HT29 cell lines.

IC50 (μM)a
Treatments HCT116 cells HT29 cells
5-FU 15.16 ± 4.20 16.45 ± 2.627
5FU + 0.5 μM 7a 7.05 ± 0.79 8.12 ± 0.14*
5FU + 1 μM 7a 6.27 ± 0.6* 7.38 ± 0.29*
5FU + 0.5 μM 7b 8.19 ± 0.05* 8.52 ± 0.49*
5FU + 1 μM 7b 7.56 ± 0.05* 6.57 ± 0.36*
a

The IC50 of 7a and 7b was determined by MTT-cell survival assay. Data is the mean ± SE of four estimations. * = Significantly different than 5-FU alone.