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IC50 of 7a and 7b with FOLFOX-HCT116, FOLFOX-HT29 and CA2 cell lines.
| IC50 (μM)a | |||
|---|---|---|---|
| Compounds | FOLFOX-HCT116 cells | FOLFOX-HT29 cells | CA2 cells |
| 7a | 5.50 ± 0.20 | 3.08 ± 0.09 | 7.96 ± 1.03 |
| 7b | 2.38 ± 0.25 | 2.59 ± 0.28 | 9.06 ± 0.71 |
The IC50 of 7a and 7b was determined by MTT-cell survival assay with FOLFOX-HCT116 and FOLFOX-HT-29 cell lines and by spheroid formation assay with CA2 cells. Data is the mean ± SE of three estimations.
