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Mouse immunogenicity study with adjuvant aluminum hydroxide
| Group | Test article | Dose (μg) | # Mice/day of blood sampling |
|||||
|---|---|---|---|---|---|---|---|---|
| Day 0a | Day 15a | Day 30a | Day 45a | Day 60 | Day 75 | |||
| 1 | ΔTM S | 1 | – | 8 | 8 | 8 | 8 | 8 |
| 2 | ΔTM S | 1 + alum | – | 8 | 8 | 8 | 8 | 8 |
| 3 | ΔTM S | 5 | – | 8 | 8 | 8 | 8 | 8 |
| 4 | ΔTM S | 5 + alum | – | 8 | 8 | 8 | 8 | 8 |
| 5 | FL His-tag | 5 | – | 8 | 8 | 8 | 8 | 8 |
| 6 | ΔTM S | 50 | – | 8 | 8 | 8 | 8 | 8 |
| 7 | Alhydrogel | – | – | 4 | 4 | 4 | 4 | 4 |
| 8 | Vehicle | – | 4 | – | 4 | – | – | 4 |
Dose day.
