Table 2.
Clinical and demographic comparisons of RSV-positive and RSV-negative children.
| Total N = 3168 | RSV-positive N = 1397 | RSV-negative N = 1771 | p-Value |
|---|---|---|---|
| Age (months) median | 3.5 months | 3.5 months | 0.16 |
| 0–1 months | 135 (10%) | 248 (14%) | <0.01 |
| 2–5 months | 736 (53%) | 772 (44%) | |
| 6–11 months | 327 (23%) | 394 (22%) | |
| 12–23 months | 199 (14%) | 357 (20%) | |
| Sex (male) | 834 (60%) | 1078 (61%) | 0.50 |
| Daycare** | 27 (2%) | 23 (1%) | 0.16 |
| Breastfeeding | 1200 (86%) | 1461 (82%) | 0.01 |
| No past medical history | 1286 (92%) | 1507 (85%) | <0.01 |
| Smoke exposure | 1070 (77%) | 1355 (77%) | 0.96 |
| Antibiotics prior to hospitalization | 653 (47%) | 633 (36%) | <0.01 |
| Antibiotics during hospitalizationa | 1279 (92%) | 1612 (92%) | 0.61 |
| Gestational Age Median % < 37 weeks |
179 (13%) | 271 (15%) | 0.046 |
| Birth weight (median, kg)• | 3.0 | 3.0 | 0.074 |
| Admission diagnosis | |||
| Bronchiolitis | 374 (27%) | 173 (10%) | <0.01 |
| Bronchopneumonia | 476 (34%) | 544 (31%) | 0.045 |
| Pneumonia | 225 (16%) | 169 (10%) | <0.01 |
| Suspected sepsis | 248 (18%) | 664 (37%) | <0.01 |
| Pertussis-like cough | 129 (9%) | 96 (5%) | <0.01 |
| Presenting symptoms | |||
| Fever | 649 (46%) | 1113 (63%) | <0.01 |
| Cough | 1320 (94%) | 1046 (59%) | <0.01 |
| Shortness of breath | 1039 (74%) | 793 (45%) | <0.01 |
| Runny nose/congestion | 40 (3%) | 37 (2%) | 0.16 |
| Decrease appetite | 301 (22%) | 399 (23%) | 0.51 |
| Seizures/convulsions | 19 (1%) | 106 (6%) | <0.01 |
| Decrease activity* | 77 (20%) | 238 (36%) | <0.01 |
| Diarrhea | 69 (5%) | 248 (14%) | <0.01 |
| Vomiting | 186 (13%) | 336 (19%) | <0.01 |
| Key examination findings | |||
| Wheezing | 926 (66%) | 831 (47%) | <0.01 |
| Cyanosis | 362 (26%) | 258 (15%) | <0.01 |
| Flaring/retractions | 173 (12%) | 108 (6%) | <0.01 |
| Abnormal chest X-rayb | 1122 (82%) | 955 (60%) | <0.01 |
| Outcomes | |||
| O2 requirementc | 566 (41%) | 447 (25%) | <0.01 |
| Days on oxygen (25th, 50th, 75th, mean, standard deviation)▵ | 1 2 5 (3.76 ± 3.3) | 1 2 4 (3.28 ± 3.1) | 0.041 |
| Mechanical ventilationsd | 52 (4%) | 59 (3%) | .54 |
| ICU staye | 126 (9%) | 158 (9%) | 0.89 |
| Median length of stay (days)f | 4 | 4 | 0.2 |
| Deathd | 7 (0.5%) | 24 (1%) | 0.015 |
| Vitamin D level (ng/mL)g | 14.3 ng/mL | 18.2 ng/mL | <0.01 |
a
3147.
b
2961.
c
3137.
d
3136.
e
3140.
f
3139.
g
2688.
▵
1012.
*
n = 1044.
**
3167.
•
3166.