Table 8.

Anticonvulsant screening of compounds 116–125.

Compound No.	MES screena
	0.5 h	4 h
116	30	300
117	30	300
118	30	300
119	100	300
120	100	300
121	100	300
122	30	300
123	100	300
124	30	300
125	30	300
Phenytoin	30	30
Carbamazepine		100

Doses of 30, 100 and 300 mg/kg were administered. The figures in the table indicate the minimum dose whereby bioactivity was demonstrated in half or more of mice. The animals were examined 0.5 and 4 h after injections were given.