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Difference in the amount of transcript variants among genotypes in HBE cells. The expression of total OAS1 and that of each individual transcript variant in HBE cells with the AA (n = 6), AG (n = 3), or GG (n = 2) genotypes of rs10774671 was obtained by real-time RT-PCR. Fold-inductions of total OAS1 expression by IFN-β, and the relative mRNA amounts of each transcript over that of the p42 transcript in AA cells without stimulation of IFN-β are shown as mean ± SEM.
