Table 3.
In vitro antitumor activities of compounds 3a-3c.
| Compd. | Position | IC50(μM) |
|
|---|---|---|---|
| K562 | HepG2 | ||
| CPT | 0.07 ± 0.01 | 0.37 ± 0.06 | |
| 2m | 5 | 0.03 ± 0.01 | 0.05 ± 0.03 |
| 3a | 4 | >10 | >10 |
| 3b | 6 | 7.46 ± 1.69 | >10 |
| 3c | 7 | 4.43 ± 0.75 | 8.56 ± 0.06 |
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