Table 3.
Poultry DNA vaccination against bacteria.
| Pathogen | Host | Antigen | Route | Major immunological outcomes | References |
|---|---|---|---|---|---|
| Chlamydophila psittaci | Turkeys | MOMP | IM + IN Or ID Or IM |
Induction of IgA, IgM and IgG. Induction of lymhoproliferation. Prevention, but not always abolition, of severe clinical symptoms upon challenge. Able to circumvent maternal antibodies. | [67], [71], [87], [95], [100] |
| Campylobacter jejuni | Chickens | Flagellin | IN | Induction of antibodies in the serum and intestinal mucosa. Reduction in cecum shedding of about 2 logs on days 18–21 after challenge. | [68] |
| Avian pasteurella multocida | Chickens | OmpH and OmpA | IM | Production of serum IgG antibodies. Induction of lymphoproliferation and IFN-γ. 70–75% of survivors after challenge. | [69] |