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. 2015 Nov 25;34(2):202–211. doi: 10.1016/j.vaccine.2015.11.043

Table 3.

Poultry DNA vaccination against bacteria.

Pathogen Host Antigen Route Major immunological outcomes References
Chlamydophila psittaci Turkeys MOMP IM + IN
Or ID
Or IM
Induction of IgA, IgM and IgG. Induction of lymhoproliferation. Prevention, but not always abolition, of severe clinical symptoms upon challenge. Able to circumvent maternal antibodies. [67], [71], [87], [95], [100]
Campylobacter jejuni Chickens Flagellin IN Induction of antibodies in the serum and intestinal mucosa. Reduction in cecum shedding of about 2 logs on days 18–21 after challenge. [68]
Avian pasteurella multocida Chickens OmpH and OmpA IM Production of serum IgG antibodies. Induction of lymphoproliferation and IFN-γ. 70–75% of survivors after challenge. [69]