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. 2009 Jul 3;30(10):1805–1815. doi: 10.1016/j.peptides.2009.06.027

Table 3.

Anti-HIV-1 and -HIV-2 activity and cytostatic properties of Clematis montana lectin (CML) in human T-lymphocyte (CEM) cells.

Compound EC50 (μg/ml)
CC50 (μg/ml)
HIV-1 HIV-2
CML 11 ± 3.9 71 ± 41 >100
GNA 0.92 0.78 6.9
LRA 0.79 0.59 7.1
SCA 4.6 8 83

GNA, Galanthus nivalis agglutinin; LRA, Lycoris radiate agglutinin; SCA, Scilla campanulata agglutinin [42].

EC50 = effective concentration or concentration required to protect CEM cells against the cytopathogenicity of HIV by 50%.

CC50 = cytotoxic concentration or concentration required to reduce CEM cell viability by 50%.