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. 2011 Jul 1;46(9):4281–4288. doi: 10.1016/j.ejmech.2011.06.034

Table 3.

Drug susceptibilities of WT HIV-1 RT from subtype B for S-PMEApp 5, S-PMPApp 6, and reference compounds PMEApp 5a and PMPApp 6a.

IC50 (μM)a
S-PMEApp 5
IC50 (μM)a
PMEApp 5a
IC50 (μM)a
S-PMPApp 6
IC50 (μM)a
PMPApp 6a
WT RT 6.8 ± 2.3 7.0 ± 2.7 13.9 ± 5.4 11.3 ± 3.8
a

IC50 values were determined with recombinant RT assayed on activated calf thymus DNA and averaged (±S.D.) for at least three independent experiments.