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. 2019 Aug 2;37(47):6933–6941. doi: 10.1016/j.vaccine.2019.02.040

Fig. 3.

Fig. 3

IgG1, IgG2a, and IgG2b subtypes in sera. IgG1 titers in antisera from mice immunized with the formulation of alum, R848, CpG, AddaVax, poly (I:C), or PELC/CpG adjuvant with (A) 0.2 µg and (D) 2 µg dose of CHO-rH7 antigen. The IgG2a titers in antisera from mice immunized with the formulation of alum, R848, CpG, AddaVax, poly (I:C), or PELC/CpG adjuvant with (B) 0.2 µg and (E) 2 µg dose of CHO-rH7 antigen. The IgG2b titers in antisera from mice immunized with the formulation of alum, R848, CpG, AddaVax, poly (I:C), or PELC/CpG adjuvant with (C) 0.2 µg and (F) 2 µg dose of CHO-rH7 antigen. * indicates P < 0.05; ** indicates P < 0.01, ***, indicates P < 0.001.