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. 2018 Feb 13;36(11):1330–1344. doi: 10.1016/j.vaccine.2018.01.068

Table 3.

Goals and objectives of the 2010 National Vaccine Plan [4].

Goal 1: Develop new and improved vaccinesprioritize new vaccine targets of domestic and global public health importance
  • support research to develop and manufacture new vaccine candidates and improve current vaccines to prevent infectious diseases

  • support research on novel and improved vaccine delivery methods

  • increase understanding of the host immune system

  • support product development, evaluation, and production techniques of vaccine candidates and the scientific tools needed for their evaluation

  • improve the tools, standards, and approaches to assess the safety, efficacy, and quality of vaccines

Goal 1: Develop new and improved vaccinesprioritize new vaccine targets of domestic and global public health importance
  • support research to develop and manufacture new vaccine candidates and improve current vaccines to prevent infectious diseases

  • support research on novel and improved vaccine delivery methods

  • increase understanding of the host immune system

  • support product development, evaluation, and production techniques of vaccine candidates and the scientific tools needed for their evaluation

  • improve the tools, standards, and approaches to assess the safety, efficacy, and quality of vaccines

Goal 2: Enhance the vaccine safety system
  • ensure a robust vaccine safety scientific system that focuses on high priority areas

  • facilitate the timely integration of advances in manufacturing sciences and regulatory approaches relevant to manufacturing, inspection, and oversight to enhance product quality and patient safety

  • enhance timely detection and verification of vaccine safety signals

  • improve timeliness of the evaluation of vaccine safety signals, especially when 1) a high-priority new vaccine safety concern emerges or 2) when a new vaccine is recommended, vaccination recommendations are expanded, or during public health emergencies such as in an influenza pandemic or other mass vaccination campaign

  • improve causality assessments of vaccines and related AEFIs

  • improve scientific knowledge about why and among whom vaccine adverse reactions occur

  • improve clinical practice to prevent, identify and manage vaccine adverse reactions

  • enhance collaboration of vaccine safety activities

Goal 3: Support communications to enhance informed vaccine decision-making
  • utilize communication approaches that are based on ongoing research

  • build and enhance collaborations and partnerships for communication efforts

  • enhance delivery of timely, accurate, and transparent information to public audiences and key intermediaries (such as media, providers, and public health officials) about what is known and unknown about the benefits and risks of vaccines

  • increase public awareness of the benefits and risks of vaccines and immunization, especially among populations at risk of under-immunization

  • assure that key decision- and policy makers (e.g., third-party payers, employers, legislators, community leaders, hospital administrators, health departments) receive accurate and timely information on vaccine benefits and risks; economics; and public and stakeholder knowledge, attitudes, and beliefs

Goal 4: Ensure a stable supply of, access to, and better use of recommended vaccines in the United States
  • ensure consistent and adequate supply of vaccines for the United States

  • ensure consistent and stable delivery of vaccines for the United States

  • reduce financial barriers to vaccination

  • maintain and enhance the capacity to monitor immunization coverage for vaccines routinely administered to all age groups

  • enhance tracking of vaccine preventable diseases (VPDs) and monitoring of the effectiveness of licensed vaccines

  • educate and support health care providers in vaccination counseling and vaccine delivery for their patients and themselves

  • maintain a strong, science-based, transparent process for developing and evaluating immunization recommendations

  • strengthen the Vaccine Injury Compensation Program (VICP) and Countermeasures Injury Compensation Program (CICP)

  • enhance immunization coverage for travelers

Goal 5: Increase global prevention of death and disease through safe and effective vaccination
  • support international organizations and countries to improve global surveillance for VPDs and strengthen health information systems to monitor vaccine coverage, effectiveness, and safety

  • support international organizations and countries to improve and sustain immunization programs as a component of health care delivery systems and promote opportunities to link immunization delivery with other priority health interventions, where appropriate

  • support international organizations and countries to introduce and make available new and underutilized vaccines to prevent diseases of public health importance

  • support international organizations and countries to improve communication of evidence-based and culturally and linguistically appropriate information about the benefits and risks of vaccines to the public, providers, and policy-makers

  • support the development of regulatory environments and manufacturing capabilities that facilitate access to safe and effective vaccines in all countries

  • build and strengthen multilateral and bilateral partnerships and other collaborative efforts to support global immunization and eradication programs