Table 2.
Clinical signs and lung lesions post-BRSV challenge.
| Clinical signs (days) |
Lung lesions at day 6 | |||
|---|---|---|---|---|
| Onset (n = 6) | Peak (n = 6) | Duration (n = 6) | Extent (%) of consolidation in cranial left/right lobes per calf | |
| No vaccine | a1.4 ± 0.3 | 6.2 ± 0.7 | 18.2 ± 0.6 | 10/10; 20/15 |
| NSRS i.m. | b2.5 ± 0.3* | 7.5 ± 0.6 | 13.5 ± 2.5 | 5/5; 5/5 |
| NSRS i.m. + i.n. | 2.5 ± 0.3* | 8.7 ± 0.4* | 14.0 ± 1.5* | 5/0; 5/5 |
a
Data (onset, peak, duration) are given as mean ± SEM.
b
Stars indicate significant differences using the non-parametric Mann–Whitney U-test (p one-tailed) between the vaccinated groups (NSRS i.m. or NSRS i.m. + i.n.) and the non-vaccinated group. Onset, peak and duration were not significantly different between the NSRS i.m. and NSRS i.m. + i.n. vaccinated groups.