Fig. 8.
Effect of BPP9α on the BK-induced migration of human polymorphonuclear leukocytes (PMN) in Boyden chambers. (A) Concentration–response curves of BK without and in presence of 10 nM BPP9α. Cells in the upper compartment of the chamber were preincubated (15 min) with BPP9α and BK was given into the lower compartment. (B): The BK-induced (10−9 M) migration is dose-dependently potentiated by BPP9α in concentrations of 10−8 and 10−7 M. Results are expressed as migration index (control = 1.0) and represent mean ± S.E.M. of 3–11 experiments. Values are significantly different from control values without BPP9α: **p < 0.01, *p < 0.05 (Student's t-test).