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. 2013 Oct 30;70:703–722. doi: 10.1016/j.ejmech.2013.10.057

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Copyright © 2013 Elsevier Masson SAS. All rights reserved.

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Scheme 2 — Reagents and conditions: a. benzoyl chloride (2.2 equiv.), pyridine, CH₃CN, r.t, 12 h, 87%; b. 1 N K₂CO₃ aq., dioxane, r.t., 24 h, 23%; c. propargyl bromide (1.2 equiv.), K₂CO₃ (1.1 equiv.), DMF, r.t., 24 h, 97%.