Fig. 3.

Effects of compound 18 on the activities of HBV promoters and enhancers HepG 2 cells were transiently transfected with a constant amount of pGL3 vector (expressing firefly luciferase) as basic control, and phRL-CMV vector (expressing Renilla luciferase) as an internal control. Firefly and Renilla luciferase activities were assayed using the Dual-Luciferase^® reporter assay System. Data represent the average ± standard deviation of triplicated samples. Normalized fold change in activity between test groups: Fold activity = compound 18 (10 μM) treated group promoter activity/mock-treated group promoter activity.