Table 7.

Sequence of reisolated vaccine viruses that showed S1 gene sequence differences from the original vaccine sequence

Vaccine	Nucleotide position	Nucleotide change	Amino acid change	Amino acid deletion
Ark/Aa	127†	T → C	Tyr43His
	388†	A → G	Ser130Gly
	637†	T → G	Ser213Ala
	976†	T → A	Tyr326Asn
	1033–1035†	AAT deletion		Asn345
Ark/Bb	976†,‡	T → A	Tyr326Asn
	1033–1035†,‡	AAT deletion		Asn345
Ark/Cc	127†	T → C	Tyr43His
	388†	A → G	Ser130Gly
	637†	T → G	Ser213Ala
	968†	C → G	Thr323Arg
	976†	T → A	Tyr326Asn
	1033–1035†	AAT deletion		Asn345
Conn/Bd	172–174‡	AAT deletion		Asn58
	238‡	T → A	No
	241†	T → A	No
	1033‡	T → C	Ser345Pro
GA/Ae	662†	G → T	Ser221Thr
	988†	G → A	Gly330Arg
	1152†	C → T	No
	1438†	G → T	Lys479Asn
Mass/Bf	191†,‡	A → G	Glu64Gly
	313‡	T → C	Ser105Pro
	1469‡	C → T	Pro490Leu

^aVirus isolated at 13 days post-vaccination (dpv).

^bVirus isolated from vaccinated birds at 9 dpv and from contact birds at 13 dpv.

^cVirus isolated at 6 dpv.

^dVirus isolated from vaccinated birds at 3 dpv and from contact birds at 6 and 13 dpv.

^eVirus isolated at 3 and 9 dpv.

^fVirus isolated from vaccinated birds at 3 and 9 dpv and from contact birds at 6 and 13 dpv.

^†Vaccinated birds.

^‡Contact birds.