Table 1.
Non-silent mutations found in the VicS-del structural protein gene region compared to VicS-v.
| Genome region | Locationa | Nucleotide change | Predicted amino acid change (locationb) |
|---|---|---|---|
| S1 | 287 | A to C | Gluc to Ala (96) |
| 408 | A to G | Ile to Met (136) | |
| 1029 | A to T | Lys to Asn (343) | |
| 1082 | A to G | Asp to Gly (361) | |
| 1237 | C to T | Arg to Cys (413) | |
| S2 | 2066 | C to A | Pro to His (149) |
| 3102 | A to T | Leu to Phe (494) | |
| M | 4718 | G to A | Arg to Gln (189) |
| ORF 4b | 4853 | T deletion | frameshift/truncation |
| ORF 4c | 5050 | G to A | Arg to Gln (10) |
| 5192 | G to T | termination to Tyr (57) | |
| 5a | 5192 | G to T | Ser to Ile (6) |
| 5200 | G to A | Gly to Ser (9) | |
| 5219 | A to G | Tyr to Cys (15) | |
| N | 5697 | T to C | Val to Ala (46) |
| 6372 | C to T | Thr to Met (271) | |
| 3′ UTR | 6794 | 40 bp deletion | truncation |
a
Location of nucleotide change relative to the S gene initiation codon.
b
Location of the amino acid change relative to the initiation codon of each gene/ORF.
c
Three letter amino acid code.